A peptide that signals your pituitary gland to make more of your own growth hormone. Here is what it does, what we don't know yet, and who it isn't for.
From $199 / month(includes provider review, medication and shipping)
Sermorelin is a lab-made version of the first 29 amino acids of growth hormone–releasing hormone (GHRH), a signal naturally produced by your brain. Rather than artificially replacing growth hormone, it signals your pituitary gland to release its own. This allows your body's usual feedback controls to function as intended. How your body responds can vary, and sermorelin is still a prescription medication with potential side effects. A licensed healthcare provider must determine whether it is appropriate for you.
Your provider decides which form fits you.
We separate what's well supported from what isn't. You deserve to know which is which before you decide.
If any of these apply to you, a provider will not prescribe Sermorelin. This isn't us being overly cautious. For these situations, the risk isn't worth it.
Not sure whether something applies to you? Start the consultation anyway. A licensed provider reviews every answer and will tell you plainly if Sermorelin isn't a fit.
Most people have mild reactions at most. Here's the full picture, sorted by what you should do about it.
Your provider needs your complete list: prescriptions, over-the-counter medicines, and supplements. They can't catch an interaction they don't know about.
General information, not a complete list. Your provider reviews your specific medications.
Everyone responds differently. This is the typical shape, not a promise.
Injection-site reactions, flushing, and vivid dreams are most likely now.
Your provider may check in or order labs to see how your body is responding.
A good point to review with your provider whether to continue.
Long-term use should be reviewed regularly, including whether you still need it.
Your provider decides whether you need labs and when. For Sermorelin, the markers they most often look at are IGF-1 (is it working, and is it too high?), fasting glucose, and thyroid function. If your provider orders labs, they'll tell you what's needed before you commit.
Cash-pay only, with no insurance claims. Payment does not guarantee a prescription. Your card is authorized at checkout and charged only if a licensed provider prescribes. If nothing is prescribed, the hold is released.
Billed per your chosen plan until you cancel. Every plan includes:
Cancel anytime by selecting “Cancel Subscription” in your patient portal, at least 48 hours before your next billing date. If a charge goes through after a successful cancellation, it will be refunded. See the Cancellation & Refund Policy.
No. HGH is growth hormone itself. Sermorelin is a signal that asks your pituitary to release more of your own, and your body's normal feedback controls stay in place. It's a different prescription with a different risk profile.
Your provider decides which form fits you. Injections are the more established form. Ask your provider about the trade-offs during your consultation.
No. The Sermorelin you receive is compounded by a licensed U.S. pharmacy. Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, efficacy, or quality. That's why provider oversight and pharmacy standards matter.
There's no known direct interaction, and they work on different systems. Your provider will decide whether combining them makes sense for you.
More in the full FAQ.
A short online consultation, reviewed by a licensed provider. If it's not a fit, they'll tell you.
Sermorelin is a compounded medication. Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, efficacy, or quality. Sermorelin requires a prescription from a licensed provider, who decides whether it is appropriate for you. Payment does not guarantee a prescription. Care is provided by independent licensed providers of the medical group assigned to you. Individual results vary. This page is educational and is not medical advice. Content last reviewed: October 30, 2026, by Jerome D. Chao, MD, FACS, and Rebecca A. Harrica, RPA-C.