A more informed approach to weight loss. Weight management is about more than willpower. Biology, appetite, health conditions, medications, and many other factors can influence a person's weight.
From $239 / month(includes provider review, medication and shipping)

For eligible patients, GLP-1 and GLP-1/GIP medications may be an option for chronic weight management. They work on hormone pathways involved in appetite, food intake, and blood sugar regulation, which can help people feel fuller and eat less.
What's the difference? GLP-1 medications, such as semaglutide, act on the GLP-1 receptor. Tirzepatide acts on both GLP-1 and GIP receptors. Both are used alongside reduced-calorie eating and increased physical activity. Individual results vary, and no specific outcome can be guaranteed.
Is medication right for you? These prescription treatments are not appropriate for everyone. A qualified healthcare professional will review your medical history, weight-related health conditions, current medications, treatment goals, and potential risks before determining whether a medication is appropriate.
Your provider decides which medication and form fit you.


Oral semaglutide, oral tirzepatide, microdosed semaglutide and microdosed tirzepatide are also available. Your provider will explain which option is best for you.
We separate what's well supported from what isn't. You deserve to know which is which before you decide.
These prescription treatments are not appropriate for everyone. Your provider will review the complete prescribing information with you.
Not sure whether something applies to you? Start the consultation anyway. A licensed provider reviews every answer and will tell you plainly if a GLP-1 isn't a fit.
Nausea, constipation, diarrhea, and other gastrointestinal side effects can occur, particularly when starting treatment or increasing the dose. Here's the full picture, sorted by what you should do about it.
Your provider needs your complete list: prescriptions, over-the-counter medicines, and supplements. They can't catch an interaction they don't know about.
General information, not a complete list. Your provider reviews your specific medications.
Everyone responds differently. This is the typical shape, not a promise.
Treatment typically starts at a lower dose and increases gradually as directed by your prescriber. This helps your body adjust and can reduce gastrointestinal side effects.
Some people notice changes in appetite within the first few weeks, while weight changes take time.
Doses are often increased gradually, so the early treatment period is not necessarily an indication of your eventual results.
Some weight regain is common after stopping. Discuss long-term treatment, alternatives, and follow-up with your provider before stopping.
Your provider decides whether you need labs and when, based on your health history. Never increase your dose or change your schedule without guidance from your prescriber. Adequate nutrition, sufficient protein, resistance exercise, and clinical monitoring can help support muscle during weight loss.
Cash-pay only, with no insurance claims. Payment does not guarantee a prescription. Your card is authorized at checkout and charged only if a licensed provider prescribes. If nothing is prescribed, the hold is released.
Billed per your chosen plan until you cancel, with lower monthly costs on 3-, 6- and 12-month plans. Your price depends on what your provider prescribes.
Every price includes review by a licensed U.S. provider, your medication from a licensed U.S. pharmacy, shipping, and messaging with your care team.
Start your consultation →Cancel anytime by selecting “Cancel Subscription” in your patient portal, at least 48 hours before your next billing date. If a charge goes through after a successful cancellation, it will be refunded. See the Cancellation & Refund Policy.
Some people have a reason to use a brand-name medication. If so, your provider can consider it during your consultation. These are separate products from the compounded semaglutide and tirzepatide described above, and a licensed provider decides whether either is appropriate for you.
FDA-approved for chronic weight management in certain adults. Made by Novo Nordisk.
$1,175/month (includes provider review, medication and shipping)
FDA-approved for chronic weight management in certain adults. Made by Eli Lilly and Company.
$1,225/month (includes provider review, medication and shipping)
Compounded medications are not FDA-approved and are not the same as these brand-name products. Wegovy® is a registered trademark of Novo Nordisk A/S. Zepbound® is a registered trademark of Eli Lilly and Company. Jellyphysh is not affiliated with or endorsed by these companies.
Compounded semaglutide and tirzepatide are not. They are prepared by licensed U.S. pharmacies, and compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, efficacy, or quality. Brand-name Wegovy® and Zepbound® are FDA-approved for chronic weight management in certain adults and are different products from the compounded versions. A licensed provider decides which option, if any, is appropriate for you.
Results vary based on the medication, dose, treatment duration, health history, and individual response, and no specific result is guaranteed. Your designated healthcare provider can help establish a realistic goal for you.
Prescription weight management medications may be appropriate for adults with a BMI of 30 or higher, or a BMI of 27 or higher with a weight-related health condition, depending on the specific medication. Your licensed healthcare provider must assess your individual eligibility.
Injectable medications are generally administered under the skin on a regular schedule, often once weekly. Your provider will explain the correct injection technique, schedule, and dose for your specific prescription. Oral weight loss medications are also available. These are generally taken by mouth daily.
Yes. Medication works best as part of a broader plan that includes balanced nutrition, physical activity, adequate hydration, sleep, and ongoing medical support. Resistance training and adequate protein intake can also help support muscle during weight loss.
Weight loss can include both fat and lean tissue. Adequate nutrition, sufficient protein, resistance exercise, and clinical monitoring can help support muscle health. Your nutritional needs should be individualized, especially if your appetite decreases significantly.
Yes. Important risks can include gallbladder problems, pancreatitis, dehydration-related kidney problems, and severe gastrointestinal symptoms. See the side effects section above for when to get help.
More in the full FAQ.
A short online consultation, reviewed by a licensed provider. If it's not a fit, they'll tell you.
The semaglutide and tirzepatide offered through Jellyphysh are compounded medications. Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, efficacy, or quality. These medications require a prescription from a licensed provider, who decides whether one is appropriate for you. Payment does not guarantee a prescription. Care is provided by independent licensed providers of the medical group assigned to you. Individual results vary. This page is educational and is not medical advice. Content last reviewed: October 30, 2026, by Jerome D. Chao, MD, FACS, and Rebecca A. Harrica, RPA-C.